Friday, May 22, 2020

Stem Cell Therapy for Diabetes Essay - 1151 Words

Diabetes, or fully named Diabetes Mellitus is when a person has high blood sugar and that is cause by the lack of insulin produced by the pancreas or it is when the cells do not respond to the insulin produced, it is also according to the type of diabetes that the cause may be different from others. There are two types of diabetes, type 1 and 2. Type 2 diabetes is mostly common found in adults, to reduce the glucose level, the subject can change diet or have a lot of exercise or if that doesn’t work they will usually take a liquid medicine or pill that helps.Type 1 diabetes is mostly found in children and is mostly rare, and diet alone cannot fix this so sometimes the subject has to take doses of insulin to lower glucose levels. Diabetes†¦show more content†¦The difference between adult stem cells and embryonic stem cells are that embryonic stem cells can become any cell or organ in the body while the adult stem cell can only repair damaged tissue in organs, and so ea ch other cannot have each others specialities [2]. Stem cells as solutions or stem cell therapy is a newly founded solution and it is still very newly discovered. The solution is to get embryonic stem cells to replace the pancreas so it could produce enough insulin to lower the blood glucose level, and it can also help change the cells that could not absorb the insulin. Meanwhile adult stem cells can help repair the pancreases tissue if damaged and like is said in the before paragraph that the embryonic stem cells and adult stem cells have different specialities. Besides diabetes, there are other diseases that can be cured using stem cells. Some diseases can be cured by replacing some cells or organs with embryonic stem cells or in other cases, like heart diseases or heart attacks can be cured by reversing the effect and using the adult stem cells to repair the tissues of the heart. Embryonic stem cells and adult stem cells are part of cell culture which is when a lab grows and/or develops their own cells to be researched or to help cure other people and it would be easier than having different expensive treatments that doesn’t work.Show MoreRelatedInsulin-producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes553 Words   |  3 PagesInsulin-producing cells derived from stem cells: A potential treatment for diabetes Insulin was discovered over 75 years ago, however the complications of diabetes still produce devastating results (Bonner-Weir et al., 2006). Such complications are retinopathy, nephropathy and neuropathy which link between high blood glucose levels are now established beyond doubt (Bonner-Weir et al., 2006). Thus, ÃŽ ²-cell replacement therapy in the form of transplantation would be a great path to prevent the complicationsRead MoreThe Idea of Using Stem Cell Therapy for Medical Treatments1788 Words   |  7 Pagesidea of using stem cell therapy for medical treatments is relatively new. A great deal of research and investment has gone into developing stem cells into viable medical treatments by making them more accessible and safe to use. Stem cell therapy is showing great promise to treat before untreatable diseases like type one diabetes. The idea of using stem cell therapy for medical treatments is relatively new. A great deal of research and investment has gone into developing stem cells into viableRead MoreMedical Advances Essay1496 Words   |  6 Pageshave occurred over the course of recent decades, to treat human immunodeficiency virus (HIV), diabetes and cancer treatment vaccines. These advances have had a positive impact in developed countries throughout the recent years and are yet still enhancing. Over the next decade, one of the significant advances in healthcare science that is turning out to be very effective is the utilization of stem cells. HIV is a virus which is caused when an individual gets into contact with infected or contaminatedRead MoreAdvantages Of Human Embryonic Stem Cells1572 Words   |  7 PagesCompare advantages and disadvantages of human embryonic stem cells (hESC) for use in cellular therapy The research of human embryonic stem cells (hESC) is talked about a lot in the field of medical research, not just by the scientists, but also by politicians, religious groups, etc. The discovery of stem cells is known as a medical sensation, with its research having the potential to cure many diseases. But there are still ethical issues standing in the way of this research, and due to this, differentRead MoreStem Cells And Its Effects On The Field Of Bioengineering1445 Words   |  6 PagesStem cells has outgrown its medico-therapies in the field of bioengineering and also in the treatment of various conditions of the blood and immune system, or to cure specific cancers Since it’s a known fact that stem cells can different to specialized cells in an undifferentiated manner. As the paper states the use of insulin producing cells from human or rat adipose tissue –derived stem cells transduced with pancreatic duodenal homeobox can could cure type 1 diabetes. An altern ative is, use ofRead MoreThe world is going through great clinical developments in the field of medicine and treatment .800 Words   |  4 PagesSuccessful approaches is using originate cells to treat diseases for example Parkinsons and diabetes. So we can say that treatment utilizing stem tissues came to remedy the problem of diseases that medicine could not handle. Even though drugs deal with many illnesses, there is continue to a lot of conditions that treatment could not handle. I really believe that stem cell therapy as an effective alternative for the management of incurable ailments but exactly what is stem tissue? ?and exactly where do theyRead MoreStem Cells And Its Effects On Society909 Words   |  4 PagesStem cells are  unspecialized  cell that can both reproduce itself indefinitely and, under  proper  conditions, differentiate into specialized cells of one or more types.  (Reece, Jane B., and Lisa A.  Urry, 2011.) The term â€Å"stem cells† were fi rst seen in scientific literature in 1868, a German biologist Ernst Haeckel used this term to describe the fertilized egg that becomes an organism. On February 2, 1963 the firs piece of evidence of blood stem cells  seem, Ernest McCulloch and James Till conductedRead MoreThe Controversial Topic of Stem-Cell Research in the United States993 Words   |  4 PagesStem cell research is a fairly controversial topic in the United States. Stem cells are cells that have the potential to become certain types of cells throughout a human body. There are a few types of stem cells, which are embryonic stem cells, adult stem cells, and induced pluripotent stem cells. Embryonic stem cells are the most controversial due to the manner from which they are obtained. Embryonic stem cells are pluripotent cells gathered from the inner cell mass of a blastocyst, which is anRead MoreThe Medical Promise Of Embryonic Stem Cells1626 Words   |  7 PagesEmbryonic Stem Cells Why should people suffer from diabetes, Alzheimer’s, sickle cell anemia, leukemia, and plenty of other degenerative diseases while the cure lies in our hands? After James Thompson, a developmental biologist, reported that he had derived the first human embryonic stem cell line (Thomson), the potential of curing degenerative diseases was revealed. Ph.D. holder and deputy director of FDA’s office of Cellular, Tissue and Gene Therapies, Stephanie Simek, explains that stem cells are unspecializedRead MoreStem Cells And Its Effects On Society910 Words   |  4 Pages Stem cells are unspecialized cell that can both reproduce itself indefinitely and, under appropriate conditions, differentiate into specialized cells of one or more types. (Reece, Jane B., and Lisa A. Urry, 2011.) The term â€Å"stem cells† were first seen in scientific literature in 1868, a German biologist Ernst Haeckel used this term to describe the fertilized egg that becomes an organism. On February 2, 1963 the firs piece of evidence of blood stem cells appear, Ernest McCulloch and James Till conducted

Thursday, May 7, 2020

John Lockes Second Treatise, of Civil Government Putting...

Lockes Second Treatise, of Civil Government has the main idea of putting sovereignty into the hands of the people, and this was one of the main ideas behind the constitution. It plays in very well, the framers built the government around the people, by making it a republic. On the national level all people are represented, and as it is divided down to state, county, city, etc. the people gain more power. Albeit, there are many differing theories of the motives of the founding fathers, from Gods hand on their minds to the Burkean conservatives they are. In between those are the theories of John P. Roche and Charles A. Beard but those differ almost as much as the God and Burkean theories. Roche thought the founding fathers were†¦show more content†¦With the view point of Locke, I would fully agree with the theory of Roche, for many reasons. In the state of nature, natural law governs behavior, and each person has consent to execute that law against someone who wrongs them by b reaching their rights. But people give up these rights when they enter a civil society, in return they get a community with protection and trust, among other things. So, first of all, Locke stresses the point of trust in each other for a civil society, and in Beards theory he talks about how the framers themselves were distrustful of others and majority rule. But, Roche talks about the compromises each state delegate made when framing the constitution, and that alone breeds trust among them. Locke also believes that when the executive authority becomes too powerful, and no longer represents the people, then they should rebel and appoint a person they can trust. And if the founders are indeed greedy and self-interested politicians looking for personal gain, then Locke would only think of rebelling. But, it is very apparent that the only personal gain came as a coincidence through the compromises the framers made, and they were such a diverse group that none would have the same intere sts to be fulfilled. There were slave owners, and not slave owners, property owners and not,Show MoreRelatedThe Enlightenment And The Enlightenment907 Words   |  4 Pagesaffected the way people understood the role of government. It changed they way they think about the purpose of the government and who should govern them. Individuals did not have to accept despair. Science and reason could bring happiness and progress. Kings did not rule by divine right. They had an obligation to their subjects. Moreover, Declaration of Independence also supported the Enlightenment principles of government advocated by John Locke. John Lockes ideas that people are entitled to theirRead MoreMartin Luther, Thomas Hobbes And John Locke2526 Words   |  11 Pagesthe law. This declaration made by the powerful nations and signed by all nations strong and weak that belong to the United Nations reflects the thoughts of many earlier philosophers to include the 16th 17th Century Martin Luther, Thomas Hobbes, and John Locke. However, each philosopher -based on their times and experiences gave a different value to how men use their freedom and equality in presence of the other in a society, and in relation to political authority. As determinant of his freedom toRead MoreLockes Explanation of Creation, Value and Protection of Property5870 Words   |  24 PagesLockes Explanation of Creation, Value and Protection of Property ‘The great and chief end... of Mens uniting into Commonwealths, and putting themselves under Government, is the preservation of their property’ (Second treatise, para.124). How and why does Locke explain the creation, value and

Wednesday, May 6, 2020

The Future Of Hierarchical Management Structures Free Essays

string(118) " Creativity in Organizations There are several factors affecting creativity that have been identified by researchers\." Introduction In the 21st century, organizations have seen the need to adapt to changes taking place in the business environment (Tidd Bessant, 2011). One of the factors that has prompted change in organizations is the shifting economy. Currently, there is a shift from an industrial economy to a knowledge driven economy (Brown Osborne, 2012). We will write a custom essay sample on The Future Of Hierarchical Management Structures or any similar topic only for you Order Now The current competition between companies has changed and is more inclined to creativity than prices of goods and services. The nature of work within organizations is also transforming from repetitive pre-arranged tasks to tasks that are more cognitive and spontaneous. This also applies to the managing styles and employee expectations. Effective adaptation to these inevitable changes requires companies to encourage a creative and innovative organizational culture (Singh Waddell, 2004). There are many organizations that are being run by the hierarchical management structure, which is characterized by strict adherence to chains of command (Daft Marcic, 2010). This limits the flexibility of an organization by slowing down decision making processes. As a result, such structures limit creativity in organizations (Bilton Cummings, 2010; Tseng, 2011). With the future expected to have a higher demand on creativity and change management, it is highly likely that hierarchical organizational structures shall be replaced by structures that emphasize more on innovation and creativity. Despite the increase in the focus on creativity and innovation, it is difficult to abolish the hierarchical structure. While some companies such as Apple, Microsoft and Google stand out for having abolished hierarchical management structures, such traditional organizational approaches still remain appropriate for many companies. It is difficult for current hierarchies to self-destruct. Whether such structures shall be replaced by an innovative and creative culture in the near future is a subject of debate. In this regard, this paper discusses whether in the near future, management in organizations shall involve nurturing of creativity and innovation, which shall reduce hierarchy in organizations. Some of the areas that are covered in relation to this include changes in the global economy, factors affecting innovation in the workplace and change management in organizations. Changes and Shifts in the Global Economy According to Henry and Bruin (2011), there is an on-going shift from a traditional knowledge economy to a creative economy. Creativity, in this context, can be defined as the process by which novel ideas are created. Not long ago, creativity was confined to arts like photography, music and painting. However, many companies have started to realize that creativity can also be applied in business, albeit, in a manner that is somewhat different from that of arts and humanities. Whilst creativity in business is about developing new ideas, it also involves solving issues that affect the business operations innovatively (Burkus, 2013). The current fast moving economy has made companies push their efficiencies to the limit so as to keep up with the market competition and ensure effective delivery of goods and services to clients. To overcome the limits that knowledge based organizations have in delivering quality and satisfaction to clients, many companies are opting to differentiate themselves from their competitors by becoming innovative and creative (Brown Osborne, 2012). An example can be drawn from the use of technology over the years. For most companies, getting ahead of the competition simply required the acquisition of the latest technology that existed at the time. For instance, the invention of computer technology revolutionized record keeping, communication and other operations. Organizations that acquired and utilized this technology gained an edge over their competitors. However, the accessibility of computer technology has become easier with time and currently, almost every company utilizes it. Therefore, being ahead of the competition in business has shifted from simply acquiring computer technology to acquiring and utilizing it in a way that is creative and unique in the industry. This is points out to the fact that lack of creativity in present-day organizations can be detrimental to organizational performance. Technological development, globalization forces, increased competition, market demand and expectations have all led to the growi ng interest on nurturing employee creativity in the workplace. Some of the companies that have been known to nurture creativity and innovation include Apple, Facebook, Microsoft and Google. Even during the past recession period, entrepreneurs in Silicon Valley continued to establish start-up companies founded on creativity. According to Dervitsiotis (2011), the success of Apple has been achieved by recognizing the crucial role that innovation plays in present day businesses. To attain its business objectives, Apple Inc hires employees that are dedicated to creating innovative and unique products. With reference Jobs’ interview published in The New Yorker by Surowiecki (2011), the company has maintains its competitiveness in the computer industry by designing products that are user friendly to a wide range of customers. Some of these products include the iPod and iMac computer that were innovatively manufactured and advertised, making Apple to stand out among its competitors. As companies recognize the need to be creative in the design of their products and services, they have also realized the importance of creativity in their management. According to Von Held (2012), effective management of a creative workforce requires motivation and inclusion. Companies ought to create a culture or environment that allows employees across all ranks to feel important by encouraging them to make contributions towards organizational development. One of the ways in which this has been achieved is through encouraging open horizontal communication structures. Whereas the trend has been towards a creative and innovative work environment, critics have pointed out several setbacks that creativity and innovation can cause in an organization. One typical characteristic of innovation is the fact that it involves taking risks, which may even threaten the existence of the organization. In addition, outcomes of innovative ideas or changes within the organization are usually unknown. Whilst some innovative ideas have positive revolutionary outcomes, there are also chances of failure (Henry Bruin, 2011). Failed innovations may be detrimental to organizations, especially if the innovation involved high costs. Factors to be managed to Enhance Creativity in Organizations There are several factors affecting creativity that have been identified by researchers. According to Andriopoulos and Lowe (2000), organizational creativity is affected by the organizational culture, organizational environment, management styles and structures, skills and resources. Amabile et al. (2004) argued that creativity is influenced by employee motivation, management practices, organizational resources and group characteristics. Other factors affecting individual creativity include personality, IQ levels, capabilities and dispositions, among others. This section explains how management of these factors can enhance creativity and innovation at the workplace. Employee Motivation Researchers have established that for employees to be innovative in the organization, they ought to have the passion and drive to do so. Employee motivation can increase their passion for innovation if it is managed appropriately. As argued by Daft and Marcic (2010), employee motivation is a complex issue that is influenced by social, biological, emotional and intellectual factors. Therefore, there are several strategies that have to be effectively managed so as to keep employees motivated and encouraged to be innovative. One of the strategies that can be used by corporations to increase employee motivation is communication. While vertical communication that characterizes hierarchical management structures may be ideal in some situations, innovative organizations thrive more on horizontal communication structures (Tidd Bessant, 2011). It is necessary for the organization’s management to frequently communicate with its employees on the organization’s vision. In addition, organizations also need to recognize and reward individual innovative contributes towards the overall good of the company. Rewards motivate employees to compete constructively and as a result, encourage innovativeness and creativity. Organizational Resources According to Yazdani et al. (2011), employees are among the most important resource in the organization. Therefore, innovative organizations ought to hire employees that have the personality and intelligence needed to make creative contributions. . a classic example of a creative individual was Einstein, who made contributions in various fields are . In addition to his contributions to Physics, it is documented that he had interests in visual arts (Runco, 2010) . Other traits that human resource managers need to look for when hiring include mental flexibility, originality in thinking self-confidence and the will to take risks. Time and financial resources also have an influence on the creativity or innovation in an organization. These resources ought to be managed effectively because their availability can either support or suppress creativity of employees (Amabile et al., 2004). Organizations need to establish a â€Å"threshold of sufficiency† within which these resources can positively contribute to creativity. Once this threshold is set, companies can be able to avoid allocating either insufficient or too much time and financial resources. Organizational Environment and Culture The conduciveness of an organizational environment for creativity can be gauged from the levels of employee participation, employee freedom of expression and experimentation and other creativity stimuli available within the organization (Amabile et al., 2004). One organization that has effectively managed its culture and environment to encourage creativity among employees is Google. For instance, the company offers social amenities to employees that are not offered by other companies. These include cafe stations that offer free food for employees, rooms for exercising and entertainment rooms where employees can play several games. Whilst these amenities do not directly contribute to the profitability of the company, they create an environment that allows them focus more on their contribution towards that growth of the company without thinking about how they will cater for these needs while at work. Hierarchical barriers at Google are limited, encouraging employees to work closely and learn from each other regardless of their positions in the firm. Therefore, creating an ideal organizational environment, keeping employees motivated and allocating resources that are within the threshold of sufficiency for creativity are among the ways of encouraging creativity and innovation among employees. The Change Management Process With the inevitability of change in present day organizations, several researchers have established steps that ought to be undertaken in managing change. Reasons that necessitate change include the need to overcome challenges that are posed by the dynamism of the business environment (Kotter, 2007). The need for organizations to effectively manage change is drawn from the fact that it may affect several business stakeholders that include suppliers, employees, customers and distributors. Whereas good change management procedures and practices are likely to improve the brand position of the company, poor change management is likely to adversely affect its performance. Anderson and Anderson (2010) point out that some of the impacts of poor change management include reduction in morale among employees and a drop in the company’s competitive capability. Kotter (2007) suggested an eight-step model of managing change in an organization. In establishing this model, he identified the errors that are commonly made by leaders in initiating change and based his change management model on these errors. The eight steps presented in the table below. Table 1: Kotter’s Change Management Process Step of ManagementExplanation 1.Establishing urgencyThis involves the creation of a sense of urgency within the organization to motivate involved parties to start the change process. 2.Forming a powerful spearheading coalitionInvolves identification of organizational members to form a cross-level team that is capable of leading the rest of the company in implementing the identified change. 3.Development of the change strategyInvolves formulating a strategy for implementing the change process. This should consider all the factors influencing the change process. 4.Communicating the change strategyThe change vision should be presented to all organizational members and stakeholders that will be involved in the process. The most effective communication paths ought to be used to ensure speedy and efficient message delivery in the organization. 5.Elimination of barriersThis involves empowering a broad based action that removes barriers to the change process and targets certain elements of change in the transformation of the organization. 6.Generating short-term winsThis is achieved by setting short-term goals that contribute to a larger long-term goal. Short term wins can be generated by rewarding employees who contribute towards meeting the short-term goals to keep them motivated. 7.Consolidating the short-term gainsCredibility from several sort term wins is collected to create a bigger change. Here, a reinvigoration is brought to the process. 8.Anchoring changes into the organization.Involves reinforcement of transformations made to be part of the organizational culture. This enables the change to be passed on in case of a change in the management or when employing new members of staff. Adapted from Kotter (2007) Even though Kotter’s approach has been approved by many researchers, critics have pointed out some flaws associated with it. For instance, O’keefe argues that it assumes that changes are one-time processes that promise stability if managed meticulously. However, the existing global uncertainty does not give an assurance that the intended goals of the change will be attained (O’Keefe, 2013). According to Anderson and Anderson (2010), effective change management benefits individuals and the overall organization. It benefits individuals by enabling them to maintain or improve their morale and performance before, during and after the change process. It also increases the acceptance of employees to the change process (Andriopoulos Dawson, 2009).Benefits of change management to the organization include enabling it to respond effectively to client demands even during the change process. It also enables the company to assess its performance by comparing its state before and after implementation of the change. Ineffective change management, on the other hand, can distort the transition of the company from its old state to the intended new state. With reference to Kotter’s eight steps, inefficient change management may cause the process to stick in one of middle stages. Therefore, it is important for organizations to ensure that they avoid negative impacts associated with the change process by ensuring that it is managed effectively. Conclusion This paper has presented an in-depth discussion on the need of change and innovation in present-day organizations. While the hierarchical structure of management has several benefits, the need for organizations to adjust to the current dynamism in economic and social conditions has prompted many companies to go for management techniques that nurture creativity and innovation. Some of the organizations that have attained high levels of success through encouraging innovation and creativity include Apple and Google. The shift in the global economy from knowledge to creativity has also been extensively discussed, which also explains why hierarchical management structures are likely to be less evident. Among the factors that have to be effectively managed to enhance creativity are employee motivation, the organizational culture and the organization’s resources. Steps to be undertaken in managing change as suggested by several researchers have also been extensively discussed. References Amabile, T. M., Schatzel, E. A., Moneta, G.B. Kramer, S.J., 2004. Leader behaviors and the work environment for creativity: perceived leader support. Leadership Quarterly , 15(1), pp.5-32. Anderson, D. Anderson, L?. A., 2010. Beyond Change Management: How to Achieve Breakthrough Results Through Concious Change Leadership. New Jersey: John Wiley Sons. Andriopoulos, C. Dawson, P., 2009. Managing Change, Creativity and Innovation. London: Sage Publications Ltd. Andriopoulos, C. Lowe, A., 2000. Enhancing organisational creativity: the process of perpetual challenging. Management Decision, 38(10), pp.734-42. Bilton, C. Cummings, S?., 2010. Creative Strategy: Reconnecting Business and Innovation. West Sussex: John Wiley Sons. Brown, K. Osborne, S?. P., 2012. Managing Change and Innovation in Public Service Organizations. Oxford: Routledge. Burkus, D., 2013. 10 Practices from the Most Innovative Organizations. [Online] Available at:http://www.creativitypost.com/business/10_practices_from_the_most_innovative_organizations [Accessed 3 November 2013]. Coy, C., 2013. Office hierarchies – which one is best for your business{viewed on 28th November 2013} available from http://www.cornerstoneondemand.com/blog/office- hierarchies#.Updr99KshsI Daft, R.L. Marcic, D?., 2010. Understanding Management. Mason: Cengage Learning. Dervitsiotis, K.N., 2011. The challenge of adaptation through innovation based on the quality of the innovation process. Total Quality Management Business Excellence, 22(5), pp.553-66. Von Held, F., 2012. Collective Creativity: Exploring Creativity in Social Network Development as Part of Organizational learning. Munich: Springer. Henry, C. de Bruin, A?., 2011. Entrepreneurship and the Creative Economy: Process, Practice and Policy. Glos: Edward Elgar Publishing. Hinks, G., 2013. The failure of ‘hierarchical’ management structures. [viewed on 28th November 2013] available from http://www.financialdirector.co.uk/financial- director/feature/2282581/the-failure-of-hierarchical-management-structures Kottler, J., 2011. Hierarchy and network: two structures, one organization. Harvard Business Review. {viewed on 28th November 2013} available from http://blogs.hbr.org/2011/05/two-structures-one-organizatio/ Kotter, J.P., 2007. Leading Change: Why Transformation Efforts Fail. Harvard Business Review, pp.1-10. Kreitner, R. Cassidy, ?C. M., 2011. Management. Mason: Cengage Learning. Lawrence, J., 2013. Conflict in the matrix – the challenges of moving away from hierarchicalstructures. {Viewed on 28th November 2013} available from http://www.hrzone.com/topic/strategies/conflict-matrix-challenges-moving-away- hierarchical-structures/139398 O’Keefe, K., 2013. Where Kotter’s 8 Steps Gets it Wrong. [Online] Available at: http://www.executiveboard.com/communications-blog/where-kotters-8-steps-gets-it-wrong/ [Accessed 3 November 2013]. Runco, M.A., 2010. Creativity: Theories and Themes: Research, Development, and Practice. Oxford: Elsevier. Singh, M. Waddell, D?., 2004. E-business Innovation and Change Management. London: Idea Group Inc (IGI). Surowiecki, J., 2011. How Steve Jobs Changed. [Online] Available at:http://www.newyorker.com/talk/financial/2011/10/17/111017ta_talk_surowiecki [Accessed 3 November 2013]. Tidd, J. Bessant, J?., 2011. Managing Innovation: Integrating Technological, Market and Organizational Change. New Jersey: John Wiley Sons. Tseng, S.-M., 2011. The effects of hierarchical culture on knowledge management processes. Management Research Review, 34(5), pp.595-608. Yazdani, B.O., Yaghoubi, N.M. Giri, E.S., 2011. Factors affecting the Empowerment of Employees. European Journal of Social Sciences, 20(2), pp.267-74. How to cite The Future Of Hierarchical Management Structures, Essay examples